Health & Wellness

13 Foods to Avoid while Taking Fosamax

Looking for foods to avoid while taking fosamax. Millions of people worldwide have osteoporosis, a disorder characterized by weakening bones and a higher susceptibility to fractures. Healthcare specialists frequently recommend drugs like Fosamax (alendronate), which helps strengthen bones and lowers the chance of fractures, to treat this crippling condition. But it’s important to realize that some dietary choices may decrease Fosamax’s effectiveness or result in undesirable side effects.

In this article, we explore the foods that should be avoided when taking Fosamax medication as we look into osteoporosis care. Knowing how to use your plate wisely can improve bone health, increase medication effectiveness, and improve your general well-being.

In This Article

  1. Foods to Avoid while Taking Fosamax

Foods to Avoid while Taking Fosamax

Here we have listed what can you not take with Fosamax:

Foods to Avoid while Taking Fosamax

1. Dairy products

If you’re taking Fosamax, avoiding dairy products (milk, cheese, yogurt) from your dose is essential. Dairy has a high calcium content which can interfere with the absorption of Fosamax when taken together. For best results, take your dose on an empty stomach and don’t consume any calcium-rich foods before or after taking it.

2. Iron Supplements

Iron supplements and Fosamax should not be taken together as they can form complexes in the gastrointestinal tract, reducing their absorption and effectiveness. To get the most out of your medication, make sure you are taking them separately or avoiding iron supplements altogether!

3. Coffee

Drinking coffee or other caffeinated beverages around the same time as taking Fosamax (alendronate) may reduce its effectiveness. This is because polyphenols, compounds found in coffee and tea, can bind to the drug and decrease its absorption in the body.

Studies have shown this to be true for people who take Fosamax to treat osteoporosis. So if you’re on this medication, it’s best not to drink your favorite cup of joe simultaneously!

4. Grapefruit and grapefruit juice

Foods to avoid with Fosamax are Grapefruit and grapefruit juice. It contains compounds called furanocoumarins that can interfere with the metabolism of Fosamax (alendronate). These compounds inhibit an enzyme in the liver called CYP3A4, responsible for breaking down medications in the body.

If this enzyme is inhibited, it could lead to higher levels of Fosamax or reduced effectiveness if not properly metabolized. So it’s best to avoid eating/drinking these when taking this medication!

5. Carbonated Beverages

I’m sure you’ve heard about the potential interference of carbonated beverages with Fosamax, a medication that requires adequate calcium absorption for optimal effectiveness.

It’s important to remember that these drinks contain phosphoric acid, which can bind with calcium and form insoluble compounds reducing its absorption from the digestive system. So it’s best to avoid consuming carbonated beverages while taking Fosamax to ensure the maximum effectiveness of this medication.

6. Soy Products

There’s a recommendation to avoid or limit soy products while taking Fosamax. This is because of compounds called phytates, found in certain plant-based foods like soybeans, which can bind with calcium and reduce absorption.

Since Fosamax helps treat osteoporosis by promoting calcium absorption, we must ensure we don’t interfere with this process by overeating food containing phytates.

7. Fatty foods

If you’re taking Fosamax, avoiding or limiting fatty foods is best. This is because they can interfere with the absorption of the medication and reduce its effectiveness.

The best way to take Fosamax is on an empty stomach in the morning with a glass of water for at least 30 minutes before consuming any food, beverages, or other medications.

8. Alcohol

Fosamax can irritate the lining of your stomach and esophagus, potentially causing heartburn, indigestion, and even stomach ulcers.

Alcohol consumption may also increase these risks when combined with Fosamax, as it, too, can irritate the stomach. Additionally, both alcohol and Fosamax affect liver function, so combining them could lead to a further burden on your liver which in turn could affect its ability to metabolize medications effectively.

9. Salt

High-sodium diets can increase the risk of bone loss and osteoporosis. It’s a good idea to moderate your sodium intake for optimal health.

Additionally, if you take Fosamax medication, ensure you get enough calcium and vitamin D in your diet for additional bone support – plus all those other essential nutrients! Let’s take care of our bodies together to stay strong and healthy!

10. Fast food and Processed snacks

Fast foods are often low in essential nutrients like calcium, vitamin D, and other minerals essential for bone health. Since Fosamax is used to treat osteoporosis, it’s crucial to maintain an adequate nutrient intake so the medication can work effectively.

Excessive sodium consumption isn’t good either, as it increases calcium excretion through the kidneys, further contributing to bone loss. Let’s reduce factors promoting bone loss by eating a balanced diet with plenty of fresh fruits and vegetables!

11. Spicy foods

While taking Fosamax (alendronate), avoiding spicy foods is best as they can directly interact with the medication.

It’s also important to note that even if your body isn’t affected by this direct interaction, some people find that eating spicy food can worsen gastrointestinal side effects of Fosamax, such as heartburn, acid reflux, and dysphagia.

12. Sugary beverages

We must be mindful of what we drink when taking medications like Fosamax. While it may be tempting to reach for a sugary beverage, these should generally be avoided as they can interfere with the absorption process and decrease the effectiveness of your medication. Instead, opt for nutrient-rich drinks such as milk or fortified plant-based milk to help keep your bones strong!

13. Licorice

I am letting you know about a compound found in licorice called glycyrrhizin. Unfortunately, studies have shown that it can decrease bone mineral density and increase the breakdown of bone tissue.

This can be especially harmful to those taking Fosamax or other medications for osteoporosis. So if you want to take care of your bones, avoiding consuming too much licorice is best!

Q. What happens if you take food with Fosamax?

Ans- If you take Fosamax with food, it can reduce the effectiveness of the medication. Calcium-rich food binds to Fosamax in your stomach and intestines, making it harder for your body to absorb all its benefits.

Q. Can you drink coffee after taking Fosamax?

Ans- Coffee may interfere with the absorption of Fosamax and reduce its effectiveness. Substances in coffee, such as calcium, can bind to the medication and hinder its absorption into your body. Therefore, it is advisable to wait at least 30 minutes after taking Fosamax before having your coffee or other beverages or foods.


In conclusion, it’s essential to be aware of specific foods that may impair bone health or interfere with the absorption of Fosamax or any other osteoporosis prescription when using it. You can maximize the effects of Fosamax and aid your journey to better bone health by avoiding or ingesting these items in moderation.


  1. Bisphosphonates: Mechanism of Action and Role in Clinical Practice
  2. Alendronate Sodium in the Management of Osteoporosis
  3. Alendronate Sodium (fosamax)

Dr Maria

MD. Board Certified physician. Fellowship In Family Medicine UK. 8 years of medical experience in Lifestyle-related health disorders. Graduated from AIIMS – All India Institute Of Medical Science, INDIA

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